The Need for Biomarkers in the ALS–FTD Spectrum: A Clinical Point of View on the Role of Proteomics

Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are severely debilitating and progressive neurodegenerative disorders. A distinctive pathological feature of several neurodegenerative diseases, including ALS and FTD, is the deposition of aberrant protein inclusions in neuronal c...

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Bibliographic Details
Main Authors: Francesca Vignaroli, Angelica Mele, Giacomo Tondo, Veronica De Giorgis, Marcello Manfredi, Cristoforo Comi, Letizia Mazzini, Fabiola De Marchi
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Proteomes
Subjects:
Online Access:https://www.mdpi.com/2227-7382/11/1/1