Signalling crosstalk during early tumorigenesis in the absence of Polycomb silencing.
In response to stress and injury a coordinated activation of conserved signalling modules, such as JNK and JAK/STAT, is critical to trigger regenerative tissue restoration. While these pathways rebuild homeostasis and promote faithful organ recovery, it is intriguing that they also become activated...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5794193?pdf=render |