Molecular modeling simulation studies reveal new potential inhibitors against HPV E6 protein.

High-risk strains of human papillomavirus (HPV) have been identified as the etiologic agent of some anogenital tract, head, and neck cancers. Although prophylactic HPV vaccines have been approved; it is still necessary a drug-based treatment against the infection and its oncogenic effects. The E6 on...

Full description

Bibliographic Details
Main Authors: Joel Ricci-López, Abraham Vidal-Limon, Matías Zunñiga, Verónica A Jimènez, Joel B Alderete, Carlos A Brizuela, Sergio Aguila
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213028