Protein variants form a system of networks: microdiversity of IMP metallo-beta-lactamases.

Genome and metagenome sequencing projects support the view that only a tiny portion of the total protein microdiversity in the biosphere has been sequenced yet, while the vast majority of existing protein variants is still unknown. By using a network approach, the microdiversity of 42 metallo-β-lact...

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Bibliographic Details
Main Authors: Michael Widmann, Jürgen Pleiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4094381?pdf=render