Diagnostic Yield of a Targeted Next-Generation Sequencing Gene Panel for Pediatric-Onset Movement Disorders: A 3-Year Cohort Study

Diagnostic Yield of a Targeted Next-Generation Sequencing Gene Panel for Pediatric-Onset Movement Disorders: A 3-Year Cohort Study

In recent years, genetic techniques of diagnosis have shown rapid development, resulting in a modified clinical approach to many diseases, including neurological disorders. Movement disorders, in particular those arising in childhood, pose a diagnostic challenge. First, from a purely phenomenologica...

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Bibliographic Details
Main Authors: Federica Graziola, Giacomo Garone, Fabrizia Stregapede, Luca Bosco, Federico Vigevano, Paolo Curatolo, Enrico Bertini, Lorena Travaglini, Alessandro Capuano
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Genetics
Subjects:
dystonia
chorea
neurodegeneration with brain iron accumulation disorders
genetics
next-generation sequencing
children
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.01026/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.01026/full

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