The role of p2x7 receptor in infectious inflammatory diseases and the influence of ectonucleotidases

The purinergic receptor P2X ligand-gated ion channel 7 (P2X7) is ubiquitously expressed in almost all tissues and organs of the body with the highest distribution in the immune cells of monocyte-macrophage origin. Classically, P2X7 receptor is involved in apoptotic cell death, and it is well known t...

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Bibliographic Details
Main Authors: Ana Carolina Morandini, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Biomedical Journal
Subjects:
Online Access:http://www.biomedj.org/article.asp?issn=2319-4170;year=2014;volume=37;issue=4;spage=169;epage=177;aulast=Morandini