A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme.

BACKGROUND:Low muscle mass and function have been associated with poorer indicators of physical capability in older people, which are in-turn associated with increased mortality rates. The growth hormone/insulin-like growth factor (GH/IGF) axis is involved in muscle function and genetic variants in...

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Main Authors: Tamuno Alfred, Yoav Ben-Shlomo, Rachel Cooper, Rebecca Hardy, Cyrus Cooper, Ian J Deary, Tom R Gaunt, David Gunnell, Sarah E Harris, Meena Kumari, Richard M Martin, Avan Aihie Sayer, John M Starr, Diana Kuh, Ian N M Day, HALCyon study team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3254646?pdf=render