ANCA-negative EGPA: only eosinophils without vasculitis? Insights from anti-T2 biologics

ANCA-negative EGPA: only eosinophils without vasculitis? Insights from anti-T2 biologics

The pathogenic role of p-ANCA in eosinophilic granulomatosis with polyangiitis (EGPA) is a long-standing matter of debate. In this work, we report our real-life experience with EGPA patients, treated with biologics targeting type 2 (T2)-eosinophilic inflammation (Mepolizumab, Benralizumab, Dupilumab...

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Bibliographic Details
Main Authors: Mario Andrea Piga, Paolo Fraticelli, Leonardo Antonicelli, Maria Stella Garritani, Giulia Ghirelli, Matteo Martini, Angelica Di Vincenzo, Maria Giovanna Danieli, Gianluca Moroncini, Maria Beatrice Bilò
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
ANCA
biologics
EGPA
eosinophils
vasculitis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1325299/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1325299/full

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