Cerebellar nuclei cells produce distinct pathogenic spike signatures in mouse models of ataxia, dystonia, and tremor

Cerebellar nuclei cells produce distinct pathogenic spike signatures in mouse models of ataxia, dystonia, and tremor

The cerebellum contributes to a diverse array of motor conditions, including ataxia, dystonia, and tremor. The neural substrates that encode this diversity are unclear. Here, we tested whether the neural spike activity of cerebellar output neurons is distinct between movement disorders with differen...

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Bibliographic Details
Main Authors: Meike E van der Heijden, Amanda M Brown, Dominic J Kizek, Roy V Sillitoe
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-07-01
Series:eLife
Subjects:
cerebellum
ataxia
dystonia
tremor
classifier model
optogenetics
Online Access:https://elifesciences.org/articles/91483

Internet

https://elifesciences.org/articles/91483

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