Pyridine Nucleotide Coenzyme Specificity of p-Hydroxybenzoate Hydroxylase and Related Flavoprotein Monooxygenases

Pyridine Nucleotide Coenzyme Specificity of p-Hydroxybenzoate Hydroxylase and Related Flavoprotein Monooxygenases

p-Hydroxybenzoate hydroxylase (PHBH; EC 1.14.13.2) is a microbial group A flavoprotein monooxygenase that catalyzes the ortho-hydroxylation of 4-hydroxybenzoate to 3,4-dihydroxybenzoate with the stoichiometric consumption of NAD(P)H and oxygen. PHBH and related enzymes lack a canonical NAD(P)H-bindi...

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Bibliographic Details
Main Authors: Adrie H. Westphal, Dirk Tischler, Florian Heinke, Sarah Hofmann, Janosch A. D. Gröning, Dirk Labudde, Willem J. H. van Berkel
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
Subjects:
Actinobacteria
coenzyme specificity
fingerprint sequence
flavoprotein
monooxygenase
NAD(P)H
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03050/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.03050/full

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