Seizures elevate gliovascular unit Ca2+ and cause sustained vasoconstriction

Seizures can result in a severe hypoperfusion/hypoxic attack that causes postictal memory and behavioral impairments. However, neither postictal changes to microvasculature nor Ca2+ changes in key cell types controlling blood perfusion have been visualized in vivo, leaving essential components of th...

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Bibliographic Details
Main Authors: Cam Ha T. Tran, Antis G. George, G. Campbell Teskey, Grant R. Gordon
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-10-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.136469