Misidentification of runs of homozygosity islands in cattle caused by interference with copy number variation or large intermarker distances

Misidentification of runs of homozygosity islands in cattle caused by interference with copy number variation or large intermarker distances

Abstract Background Runs of homozygosity (ROH) islands are stretches of homozygous sequence in the genome of a large proportion of individuals in a population. Algorithms for the detection of ROH depend on the similarity of haplotypes. Coverage gaps and copy number variants (CNV) may result in incor...

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Main Authors: Wilson Nandolo, Yuri T. Utsunomiya, Gábor Mészáros, Maria Wurzinger, Negar Khayadzadeh, Rafaela B. P. Torrecilha, Henry A. Mulindwa, Timothy N. Gondwe, Patrik Waldmann, Maja Ferenčaković, José F. Garcia, Benjamin D. Rosen, Derek Bickhart, Curt P. van Tassell, Ino Curik, Johann Sölkner
Format: Article
Language:deu
Published: BMC 2018-08-01
Series:Genetics Selection Evolution
Online Access:http://link.springer.com/article/10.1186/s12711-018-0414-x

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http://link.springer.com/article/10.1186/s12711-018-0414-x

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