Prevalence of neurotoxicity symptoms among postpartum women on isoniazid preventive therapy and efavirenz-based treatment for HIV: an exploratory objective of the IMPAACT P1078 randomized trial

Prevalence of neurotoxicity symptoms among postpartum women on isoniazid preventive therapy and efavirenz-based treatment for HIV: an exploratory objective of the IMPAACT P1078 randomized trial

Abstract Background This exploratory analysis investigates the prevalence and risk factors of neurocognitive toxicity in postpartum women on HIV treatment in response to a concern of an Isoniazid Preventive Therapy (IPT)/Efavirenz interaction. Trial Design Pregnant women on HIV treatment from countr...

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Bibliographic Details
Main Authors: Patricia Mandima, Kristin Baltrusaitis, Grace Montepiedra, Lisa Aaron, Jyoti Mathad, Carolyne Onyango-Makumbi, Mandisa Nyati, James Ngocho, Gift Chareka, Ponego Ponatshego, Gaerolwe Masheto, Katie McCarthy, Patrick Jean-Philippe, Amita Gupta, Lynda Stranix-Chibanda, for the IMPAACT P1078 T. B. APPRISE study team
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Pregnancy and Childbirth
Subjects:
Depression
Isoniazid preventive therapy
Efavirenz
Pregnant and Breastfeeding Women
PHQ-9
Online Access:https://doi.org/10.1186/s12884-022-05341-3

Internet

https://doi.org/10.1186/s12884-022-05341-3

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