Gentiopicroside improves high-fat diet-induced NAFLD in association with modulation of host serum metabolome and gut microbiome in mice

Gentiopicroside improves high-fat diet-induced NAFLD in association with modulation of host serum metabolome and gut microbiome in mice

ObjectiveThe incidence of non-alcoholic fatty liver disease is increasing every year, and there is growing evidence that metabolites and intestinal bacteria play a causal role in NAFLD. Gentiopicroside, a major iridoids compound in gentian, has been reported to reduce hepatic lipid accumulation. How...

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Bibliographic Details
Main Authors: Lijuan Wang, Yuxin Jiang, Qian Yu, Chunping Xiao, Jin Sun, Lili Weng, Ye Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Microbiology
Subjects:
Gentiopicroside
high-fat diet
non-alcoholic fatty liver
metabolome
gut microbiome
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1145430/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1145430/full

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