Pigment Epithelia of the Eye: Cell-Type Conversion in Regeneration and Disease

Pigment epithelial cells (PECs) of the retina (RPE), ciliary body, and iris (IPE) are capable of altering their phenotype. The main pathway of phenotypic switching of eye PECs in vertebrates and humans in vivo and/or in vitro is neural/retinal. Besides, cells of amphibian IPE give rise to the lens a...

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Bibliographic Details
Main Author: Eleonora N. Grigoryan
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/3/382