Staphylococcus aureus alpha-toxin inhibits CD8+ T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma

Staphylococcus aureus alpha-toxin inhibits CD8+ T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma

Staphylococcus aureus and its toxins have been linked to disease progression and mortality in advanced stages of cutaneous T-cell lymphoma (CTCL). CD8+ T cells play a crucial role in anti-cancer responses and high CD8+ T cell numbers in tumor lesions are associated with a favorable prognosis in CTCL...

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Bibliographic Details
Main Authors: Edda Blümel, Shamaila Munir Ahmad, Claudia Nastasi, Andreas Willerslev-Olsen, Maria Gluud, Simon Fredholm, Tengpeng Hu, Bas G. J. Surewaard, Lise M. Lindahl, Hanne Fogh, Sergei B. Koralov, Lise Mette Rahbek Gjerdrum, Rachael A. Clark, Lars Iversen, Thorbjørn Krejsgaard, Charlotte Menné Bonefeld, Carsten Geisler, Jürgen C. Becker, Anders Woetmann, Mads Hald Andersen, Terkild Brink Buus, Niels Ødum
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
alpha-toxin
staphylococcus aureus
ctcl
cd8+ t cells
cytotoxicity
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1751561

Internet

http://dx.doi.org/10.1080/2162402X.2020.1751561

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