NFAT1 Regulates Ly6Chi Monocyte Recruitment to the CNS and Plays an Essential Role in Resistance to Toxoplasma gondii Infection

NFAT1 Regulates Ly6Chi Monocyte Recruitment to the CNS and Plays an Essential Role in Resistance to Toxoplasma gondii Infection

Monocytes play key roles in the maintenance of homeostasis and in the control of the infection. Monocytes are recruited from the bone marrow to inflammatory sites and are essential for antimicrobial activity to limit tissue damage and promote adaptive T cell responses. Here, we investigated the role...

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Bibliographic Details
Main Authors: Luciana Benevides, Verônica M. Saltarelli, Franciele Pioto, Laís A. Sacramento, Murilo S. Dias, Gretel R. Rodríguez, João P. B. Viola, Vanessa Carregaro, João S. Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
inflammatory monocyte
NFAT1
T. gondii
cell migration
Th1 cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02105/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02105/full

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