Assessment of clusters of transcription factor binding sites in relationship to human promoter, CpG islands and gene expression

<p>Abstract</p> <p>Background</p> <p>Gene expression is regulated mainly by transcription factors (TFs) that interact with regulatory <it>cis</it>-elements on DNA sequences. To identify functional regulatory elements, computer searching can predict TF bindin...

Full description

Bibliographic Details
Main Authors: Sakaki Yoshiyuki, Kojima Toshio, Murakami Katsuhiko
Format: Article
Language:English
Published: BMC 2004-02-01
Series:BMC Genomics
Subjects:
Online Access:http://www.biomedcentral.com/1471-2164/5/16