Continuous Production of Human Epidermal Growth Factor Using Escherichia coli Biofilm

Continuous Production of Human Epidermal Growth Factor Using Escherichia coli Biofilm

Increasing demand for recombinant proteins necessitates efficient protein production processes. In this study, a continuous process for human epidermal growth factor (hEGF) secretion by Escherichia coli was developed by taking advantage of biofilm formation. Genes bcsB, fimH, and csgAcsgB that have...

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Bibliographic Details
Main Authors: Mengting Li, Zhenyu Wang, Miao Zhou, Chong Zhang, Kaiqi Zhi, Shuli Liu, Xiujuan Sun, Zhi Wang, Jinle Liu, Dong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Microbiology
Subjects:
Escherichia coli
biofilm formation
hEGF secretion
immobilized fermentation
biofilm-based fermentation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.855059/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.855059/full

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