Low-density lipoprotein electronegativity is a novel cardiometabolic risk factor.

Low-density lipoprotein (LDL) plays a central role in cardiovascular disease (CVD) development. In LDL chromatographically resolved according to charge, the most electronegative subfraction-L5-is the only subfraction that induces atherogenic responses in cultured vascular cells. Furthermore, increas...

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Main Authors: Jing-Fang Hsu, Tzu-Chieh Chou, Jonathan Lu, Shu-Hua Chen, Fang-Yu Chen, Ching-Chu Chen, Jeffrey L Chen, MacArthur Elayda, Christie M Ballantyne, Steven Shayani, Chu-Huang Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4159324?pdf=render