Long-Term Exposure to Temozolomide Affects Locomotor Activity and Cartilage Structure of Elderly Experimental Rats

Chemotherapy with temozolomide (TMZ) is an essential part of anticancer therapy of various malignant tumours; however, its long-term effects on patients’ health and life quality need to be further investigated. Here, we studied the effects of TMZ and/or companion drug dexamethasone (DXM) on the loco...

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Bibliographic Details
Main Authors: Anastasia V. Suhovskih, Olga P. Molodykh, Victor S. Ushakov, Maxim O. Politko, Dmitry K. Sokolov, Elena V. Koldysheva, Elvira V. Grigorieva
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/8/12/541