Whole-Section Tumor Micro-Architecture Analysis by a Two-Dimensional Phasor-Based Approach Applied to Polarization-Dependent Second Harmonic Imaging

Whole-Section Tumor Micro-Architecture Analysis by a Two-Dimensional Phasor-Based Approach Applied to Polarization-Dependent Second Harmonic Imaging

Second Harmonic Generation (SHG) microscopy has gained much interest in the histopathology field since it allows label-free imaging of tissues simultaneously providing information on their morphology and on the collagen microarchitecture, thereby highlighting the onset of pathologies and diseases. A...

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Bibliographic Details
Main Authors: Riccardo Scodellaro, Margaux Bouzin, Francesca Mingozzi, Laura D'Alfonso, Francesca Granucci, Maddalena Collini, Giuseppe Chirico, Laura Sironi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Oncology
Subjects:
second harmonic generation
phasor approach
collagen
cancer
two-photon microscopy
label-free imaging
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00527/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00527/full

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