Identification of miRNA signature associated with BMP2 and chemosensitivity of TMZ in glioblastoma stem-like cells

Identification of miRNA signature associated with BMP2 and chemosensitivity of TMZ in glioblastoma stem-like cells

Glioblastoma multiform (GBM) is the most lethal intracranial tumor in adults. Glioblastoma stem-like cells (GSCs) are responsible for tumorigenesis and chemotherapy resistance. BMPs are known to increase temozolomide (TMZ) response in GSCs, however, the intracellular molecular mechanism remains larg...

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Bibliographic Details
Main Authors: Xiaoyu Guo, Ziguo Luo, Tong Xia, Lanxiang Wu, Yanshu Shi, Ying Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-09-01
Series:Genes and Diseases
Subjects:
BMP2
Cancer stem cell
CeRNA
Gliobalstoma
RNA-seq
TMZ
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304219300674

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http://www.sciencedirect.com/science/article/pii/S2352304219300674

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