Gut Microbiota Dysbiosis Is Associated with Altered Bile Acid Metabolism in Infantile Cholestasis

ABSTRACT The co-occurrence of gut microbiota dysbiosis and bile acid (BA) metabolism alteration has been reported in several human liver diseases. However, the gut microbiota dysbiosis in infantile cholestatic jaundice (CJ) and the linkage between gut bacterial changes and alterations of BA metaboli...

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Bibliographic Details
Main Authors: Yizhong Wang, Xuefeng Gao, Xinyue Zhang, Yongmei Xiao, Jiandong Huang, Dongbao Yu, Xiaolu Li, Hui Hu, Ting Ge, Dan Li, Ting Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mSystems
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00463-19