Efficient Catalytic Oxidation of 3-Arylthio- and 3-Cyclohexylthio-lapachone Derivatives to New Sulfonyl Derivatives and Evaluation of Their Antibacterial Activities

Efficient Catalytic Oxidation of 3-Arylthio- and 3-Cyclohexylthio-lapachone Derivatives to New Sulfonyl Derivatives and Evaluation of Their Antibacterial Activities

New sulfonyl-lapachones were efficiently obtained through the catalytic oxidation of arylthio- and cyclohexylthio-lapachone derivatives with hydrogen peroxide in the presence of a Mn(III) porphyrin complex. The antibacterial activities of the non-oxidized and oxidized lapachone derivatives against t...

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Bibliographic Details
Main Authors: Mariana F. do C. Cardoso, Ana T. P. C. Gomes, Caroline dos S. Moreira, Mário M. Q. Simões, Maria G. P. M. S. Neves, David R. da Rocha, Fernando de C. da Silva, Catarina Moreirinha, Adelaide Almeida, Vitor F. Ferreira, José A. S. Cavaleiro
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Molecules
Subjects:
oxidation
porphyrinatoMn(III)
hydrogen peroxide
arylthio/cyclohexylthio-lapachones
sulfonyl-lapachones
polyvinylpyrrolidone
antibacterial activity
Online Access:http://www.mdpi.com/1420-3049/22/2/302

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http://www.mdpi.com/1420-3049/22/2/302

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