Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis

Abstract The recruitment of DRP1 to mitochondrial membranes prior to fission is facilitated by the wrapping of endoplasmic reticulum (ER) membranes around the mitochondria. To investigate the complex interplay between the ER membranes and DRP1 in the context of mitochondrial structure and function,...

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Bibliographic Details
Main Authors: Rachel J. Carter, Mateus Milani, Alison J. Beckett, Shiyu Liu, Ian A. Prior, Gerald M. Cohen, Shankar Varadarajan
Format: Article
Language:English
Published: Nature Publishing Group 2022-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04869-8