Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C.

Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C.

The ability of DENV2 to display different morphologies (hence different antigenic properties) complicates vaccine and therapeutics development. Previous studies showed most strains of laboratory adapted DENV2 particles changed from smooth to "bumpy" surfaced morphology when the temperature...

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Bibliographic Details
Main Authors: Xin-Ni Lim, Chao Shan, Jan K Marzinek, Hongping Dong, Thiam Seng Ng, Justin S G Ooi, Guntur Fibriansah, Jiaqi Wang, Chandra S Verma, Peter J Bond, Pei-Yong Shi, Shee-Mei Lok
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007996

Internet

https://doi.org/10.1371/journal.ppat.1007996

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