Functional single nucleotide polymorphisms in dopaminergic receptors D2 predict clinical response to Cariprazine

Functional single nucleotide polymorphisms in dopaminergic receptors D2 predict clinical response to Cariprazine

Cariprazine (CAR) is an antipsychotic drug for the treatment of schizophrenia (SCZ) and bipolar disorder (BD), and it acts as a partial agonist on the dopamine receptors (DR), D2, and D3. Although many single nucleotide polymorphisms (SNPs) in genes coding for these receptors are known to influence...

Full description

Bibliographic Details
Main Authors: Marco De Pieri, Marco Ferrari, Franca Marino, Rafael Traber, Emilio Bolla, Marco Cosentino
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pharmacology
Subjects:
pharmacogenetics
Cariprazine
DRD2
DRD3
personalized medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1182393/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1182393/full

Similar Items