TLR9 regulates the autophagy–lysosome pathway to promote dendritic cell maturation and activation by activating the TRAF6‐cGAS‐STING pathway

TLR9 regulates the autophagy–lysosome pathway to promote dendritic cell maturation and activation by activating the TRAF6‐cGAS‐STING pathway

Abstract Dysregulated maturation and activation of dendritic cells (DCs) play a significant role in the progression of systemic lupus erythematosus (SLE). The autophagy–lysosome pathway has been identified as a potential mechanism to inhibit DC activation and maturation, but its precise workings rem...

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Bibliographic Details
Main Authors: Ying Liu, Fang‐Zhi Wei, Yu‐Wei Zhan, Ru Wang, Bi‐Yao Mo, Shu‐Dian Lin
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
autophagy–lysosome pathway
dendritic cells
systemic lupus erythematosus
TLR9
TRAF6‐cGAS‐STING pathway
Online Access:https://doi.org/10.1002/kjm2.12769

Internet

https://doi.org/10.1002/kjm2.12769

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