TLR9 regulates the autophagy–lysosome pathway to promote dendritic cell maturation and activation by activating the TRAF6‐cGAS‐STING pathway

Abstract Dysregulated maturation and activation of dendritic cells (DCs) play a significant role in the progression of systemic lupus erythematosus (SLE). The autophagy–lysosome pathway has been identified as a potential mechanism to inhibit DC activation and maturation, but its precise workings rem...

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Autori principali: Ying Liu, Fang‐Zhi Wei, Yu‐Wei Zhan, Ru Wang, Bi‐Yao Mo, Shu‐Dian Lin
Natura: Articolo
Lingua:English
Pubblicazione: Wiley 2023-12-01
Serie:Kaohsiung Journal of Medical Sciences
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Accesso online:https://doi.org/10.1002/kjm2.12769