Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer’s Disease Potential

Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer’s Disease Potential

Marine alkaloids belonging to the lamellarins family, which incorporate a 5,6-dihydro-1-phenylpyrrolo[2,1-<i>a</i>]isoquinoline (DHPPIQ) moiety, possess various biological activities, spanning from antiviral and antibiotic activities to cytotoxicity against tumor cells and the reversal o...

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Bibliographic Details
Main Authors: Alisa A. Nevskaya, Lada V. Anikina, Rosa Purgatorio, Marco Catto, Orazio Nicolotti, Modesto de Candia, Leonardo Pisani, Tatiana N. Borisova, Almira R. Miftyakhova, Aleksey V. Varlamov, Elena Yu. Nevskaya, Roman S. Borisov, Leonid G. Voskressensky, Cosimo D. Altomare
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
acetylcholinesterase inhibitors
β-amyloid aggregation
anti-Alzheimer’s disease agents
cytotoxicity
pyrrolo[2,1-<i>a</i>]isoquinolines
Online Access:https://www.mdpi.com/1420-3049/26/2/359

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https://www.mdpi.com/1420-3049/26/2/359

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