In Silico Study of the Mechanisms Underlying the Action of the Snake Natriuretic-Like Peptide Lebetin 2 during Cardiac Ischemia

In Silico Study of the Mechanisms Underlying the Action of the Snake Natriuretic-Like Peptide Lebetin 2 during Cardiac Ischemia

Lebetin 2 (L2), a natriuretic-like peptide (NP), exerts potent cardioprotection in myocardial infarction (MI), with stronger effects than B-type natriuretic peptide (BNP). To determine the molecular mechanisms underlying its cardioprotection effect, we used molecular modeling, molecular docking and...

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Bibliographic Details
Main Authors: Hinda Allaoui, Nedra Rached, Naziha Marrakchi, Ameur Cherif, Amor Mosbah, Erij Messadi
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Toxins
Subjects:
natriuretic peptides
receptors
cardioprotection
molecular docking
molecular dynamics simulation
virtual screening
Online Access:https://www.mdpi.com/2072-6651/14/11/787

Internet

https://www.mdpi.com/2072-6651/14/11/787

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