LPS binding protein and activation signatures are upregulated during asthma exacerbations in children

LPS binding protein and activation signatures are upregulated during asthma exacerbations in children

Abstract Asthma exacerbations in children are associated with respiratory viral infection and atopy, resulting in systemic immune activation and infiltration of immune cells into the airways. The gene networks driving the immune activation and subsequent migration of immune cells into the airways re...

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Bibliographic Details
Main Authors: Anya C. Jones, Jonatan Leffler, Ingrid A. Laing, Joelene Bizzintino, Siew-Kim Khoo, Peter N. LeSouef, Peter D. Sly, Patrick G. Holt, Deborah H. Strickland, Anthony Bosco
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Respiratory Research
Subjects:
Atopic asthma
Network analysis
Bulk RNA-Seq
Peripheral blood
LPS
TGFB1
Online Access:https://doi.org/10.1186/s12931-023-02478-3

Internet

https://doi.org/10.1186/s12931-023-02478-3

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