Nephron deficit and low podocyte density increase risk of albuminuria and glomerulosclerosis in a model of diabetes

Abstract Podocytes are terminally differentiated epithelial cells in glomeruli. Podocyte injury and loss are features of many diseases leading to chronic kidney disease (CKD). The developmental origins of health and disease hypothesis propose an adverse intrauterine environment can lead to CKD later...

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Bibliographic Details
Main Authors: Sarah E. Gazzard, James van derWolde, Kotaro Haruhara, John F. Bertram, Luise A. Cullen‐McEwen
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15579