Four in one—Combination therapy using live Lactococcus lactis expressing three therapeutic proteins for the treatment of chronic non-healing wounds

Diabetes mellitus is one of the major concerns for health care systems, affecting 382 million people worldwide. Among the different complications of diabetes, lower limbs chronic ulceration is a common, severe and costly cause of morbidity. Diabetic foot ulcers are a leading cause of hospitalization...

Full description

Bibliographic Details
Main Authors: Jere Kurkipuro, Igor Mierau, Thomas Wirth, Haritha Samaranayake, Wesley Smith, Hanna-Riikka Kärkkäinen, Mirka Tikkanen, Juha Yrjänheikki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884502/?tool=EBI