Optimizing metaproteomics database construction: lessons from a study of the vaginal microbiome

Optimizing metaproteomics database construction: lessons from a study of the vaginal microbiome

ABSTRACT Metaproteomics, a method for untargeted, high-throughput identification of proteins in complex samples, provides functional information about microbial communities and can tie functions to specific taxa. Metaproteomics often generates less data than other omics techniques, but analytical wo...

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Bibliographic Details
Main Authors: Elliot M. Lee, Sujatha Srinivasan, Samuel O. Purvine, Tina L. Fiedler, Owen P. Leiser, Sean C. Proll, Samuel S. Minot, Brooke L. Deatherage Kaiser, David N. Fredricks
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mSystems
Subjects:
metaproteomics
proteomics
metagenomics
protein databases
database optimization
microbiome
Online Access:https://journals.asm.org/doi/10.1128/msystems.00678-22

Internet

https://journals.asm.org/doi/10.1128/msystems.00678-22

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