Val43 residue of NsrR is crucial for the nitric oxide response of Salmonella Typhimurium

Val43 residue of NsrR is crucial for the nitric oxide response of Salmonella Typhimurium

ABSTRACT In pathogenic bacteria, the flavohemoglobin Hmp is crucial in metabolizing the cytotoxic levels of nitric oxide (NO) produced in phagocytic cells, contributing to bacterial virulence. Hmp expression is predominantly regulated by the Rrf2 family transcription repressor NsrR in an NO-dependen...

Full description

Bibliographic Details
Main Authors: Hee Jeong Park, Hye Won Jeong, Choa Lee, Mi Rae Lee, Hojung Choi, Eungseok Kim, Iel Soo Bang
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:Microbiology Spectrum
Subjects:
flavohemoglobin Hmp
nitric oxide
NsrR
Salmonella Typhimurium
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03024-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03024-23

Similar Items