TCR-like bispecific antibodies toward eliminating infected hepatocytes in HBV mouse models

TCR-like bispecific antibodies toward eliminating infected hepatocytes in HBV mouse models

Therapeutics for eradicating hepatitis B virus (HBV) infection are still limited and current nucleos(t)ide analogs (NAs) and interferon are effective in controlling viral replication and improving liver health, but they cannot completely eradicate the hepatitis B virus and only a very small number o...

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Bibliographic Details
Main Authors: Yang Shi, Zihan Wang, Jingjing Xu, Wenxia Niu, Yubin Wu, Huiyu Guo, Jinmiao Shi, Zonglin Li, Baorong Fu, Yunda Hong, Zikang Wang, Wenjie Guo, Dabing Chen, Xingling Li, Qian Li, Shaojuan Wang, Jiahua Gao, Aling Sun, Yaosheng Xiao, Jiali Cao, Lijuan Fu, Yangtao Wu, Tianying Zhang, Ningshao Xia, Quan Yuan
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Hepatitis B virus
TCR-like antibody
bispecific antibody
therapeutic antibody
HBsAg suppression
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2387448

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2024.2387448

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