The Role of Epigenetic Modifications in Neurotoxicity Induced by Neonatal General Anesthesia

It has been widely demonstrated by numerous preclinical studies and clinical trials that the neonates receiving repeated or long-time general anesthesia (GA) could develop prolonged cognitive dysfunction. However, the definite mechanism remains largely unknown. Epigenetics, which is defined as herit...

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Bibliographic Details
Main Authors: Lin-Hui Ma, Jing Yan, Xin-Hao Jiao, Cheng-Hua Zhou, Yu-Qing Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.877263/full