The m6A regulator KIAA1429 stabilizes RAB27B mRNA and promotes the progression of chronic myeloid leukemia and resistance to targeted therapy

The m6A regulator KIAA1429 stabilizes RAB27B mRNA and promotes the progression of chronic myeloid leukemia and resistance to targeted therapy

Chronic myeloid leukemia (CML) is a common adult leukemia. Both the acute phase of the disease and the adverse effects of anti-cancer treatments can lead to a poor prognosis. The N6-methyladenine (m6A) modification plays an important regulatory role in various physiological and pathological processe...

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Bibliographic Details
Main Authors: Fangyi Yao, Fangmin Zhong, Junyao Jiang, Ying Cheng, Shuai Xu, Jing Liu, Jin Lin, Jing Zhang, Shuqi Li, Meiyong Li, Yanmei Xu, Bo Huang, Xiaozhong Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Genes and Diseases
Subjects:
Chronic myeloid leukemia
KIAA1429
N6-methyladenine
RAB27B
Rucaparib
YTHDF1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304223001411

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http://www.sciencedirect.com/science/article/pii/S2352304223001411

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