Tablet Disintegratability: Sensitivity of Superdisintegrants to Temperature and Compaction Pressure

Tablet Disintegratability: Sensitivity of Superdisintegrants to Temperature and Compaction Pressure

Tablet disintegration is an important pre-requisite for drug dissolution and absorption. The disintegration test is typically conducted at 37 °C, but the intragastric temperature may vary due to meals or fever. This study investigated the effects of temperature and compaction pressure on tablet disi...

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Bibliographic Details
Main Authors: Audrey Yi Zheng, Paul Wan Sia Heng, Lai Wah Chan
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
disintegration
temperature
superdisintegrant
swelling
strain recovery
tablet
Online Access:https://www.mdpi.com/1999-4923/14/12/2725

Internet

https://www.mdpi.com/1999-4923/14/12/2725

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