Gaseous hydrogen sulfide protects against myocardial ischemia-reperfusion injury in mice partially independent from hypometabolism.

BACKGROUND: Ischemia-reperfusion injury (IRI) is a major cause of cardiac damage following various pathological processes. Gaseous hydrogen sulfide (H2S) is protective during IRI by inducing a hypometabolic state in mice which is associated with anti-apoptotic, anti-inflammatory and antioxidant prop...

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Main Authors: Pauline M Snijder, Rudolf A de Boer, Eelke M Bos, Joost C van den Born, Willem-Peter T Ruifrok, Inge Vreeswijk-Baudoin, Marcory C R F van Dijk, Jan-Luuk Hillebrands, Henri G D Leuvenink, Harry van Goor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3651205?pdf=render