The Formin Diaphanous Regulates Myoblast Fusion through Actin Polymerization and Arp2/3 Regulation.

The formation of multinucleated muscle cells through cell-cell fusion is a conserved process from fruit flies to humans. Numerous studies have shown the importance of Arp2/3, its regulators, and branched actin for the formation of an actin structure, the F-actin focus, at the fusion site. This F-act...

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Bibliographic Details
Main Authors: Su Deng, Ingo Bothe, Mary K Baylies
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4546610?pdf=render