Evaluation of the impact of rifampicin on the plasma concentration of linezolid in tuberculosis co-infected patients

Linezolid combined with rifampicin has shown excellent clinical outcomes against infection by multi-resistant Gram-positive bacteria. However, several studies have indicated that rifampicin reduces the plasma concentration of linezolid in patients with severe infection. Linezolid has been recommende...

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Bibliographic Details
Main Authors: Pan Yan, Qun-Zhi Shi, Yi-Xing Hu, Ying Zeng, Hong Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1260535/full