Perineuronal nets are under the control of type-5 metabotropic glutamate receptors in the developing somatosensory cortex

Perineuronal nets are under the control of type-5 metabotropic glutamate receptors in the developing somatosensory cortex

Abstract mGlu5 metabotropic glutamate receptors are highly functional in the early postnatal life, and regulate developmental plasticity of parvalbumin-positive (PV+) interneurons in the cerebral cortex. PV+ cells are enwrapped by perineuronal nets (PNNs) at the closure of critical windows of cortic...

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Bibliographic Details
Main Authors: Giada Mascio, Domenico Bucci, Serena Notartomaso, Francesca Liberatore, Nico Antenucci, Pamela Scarselli, Tiziana Imbriglio, Stefano Caruso, Roberto Gradini, Milena Cannella, Luisa Di Menna, Valeria Bruno, Giuseppe Battaglia, Ferdinando Nicoletti
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01210-3

Internet

https://doi.org/10.1038/s41398-021-01210-3

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