Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

Na+/H+antiporters transport sodium or lithium ions across the membrane in exchange for protons. Here the authors combine ion mobility mass spectrometry and molecular dynamics simulations to uncover a facilitating role for lipids in the transport mechanism.

Bibliographic Details
Main Authors: Michael Landreh, Erik G. Marklund, Povilas Uzdavinys, Matteo T. Degiacomi, Mathieu Coincon, Joseph Gault, Kallol Gupta, Idlir Liko, Justin L. P. Benesch, David Drew, Carol V. Robinson
Format: Article
Language:English
Published: Nature Portfolio 2017-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13993

Internet

https://doi.org/10.1038/ncomms13993

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