Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties

Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties

Abstract Background The initiation and progression of hepatocellular carcinoma (HCC) are largely dependent on its local microenvironment. Adipocytes are an important component of hepatic microenvironment in nonalcoholic fatty liver disease (NAFLD), which is a significant risk factor for HCC. Given t...

Full description

Bibliographic Details
Main Authors: Shihua Wang, Meiqian Xu, Xiaoxia Li, Xiaodong Su, Xian Xiao, Armand Keating, Robert Chunhua Zhao
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Hematology & Oncology
Subjects:
Exosomes
Adipocyte
HCC
MSCs
NF-κB
Online Access:http://link.springer.com/article/10.1186/s13045-018-0625-1

Internet

http://link.springer.com/article/10.1186/s13045-018-0625-1

Similar Items