High fidelity epigenetic inheritance: Information theoretic model predicts threshold filling of histone modifications post replication.

During cell devision, maintaining the epigenetic information encoded in histone modification patterns is crucial for survival and identity of cells. The faithful inheritance of the histone marks from the parental to the daughter strands is a puzzle, given that each strand gets only half of the paren...

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Bibliographic Details
Main Authors: Nithya Ramakrishnan, Sibi Raj B Pillai, Ranjith Padinhateeri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-02-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1009861