Efficacy of Antibodies Targeting TfR1 in Xenograft Mouse Models of AIDS-Related Non-Hodgkin Lymphoma

Efficacy of Antibodies Targeting TfR1 in Xenograft Mouse Models of AIDS-Related Non-Hodgkin Lymphoma

Transferrin receptor 1 (TfR1), also known as CD71, is a transmembrane protein involved in the cellular uptake of iron and the regulation of cell growth. This receptor is expressed at low levels on a variety of normal cells, but is upregulated on cells with a high rate of proliferation, including mal...

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Bibliographic Details
Main Authors: Tracy R. Daniels-Wells, Pierre V. Candelaria, Emiko Kranz, Jing Wen, Lan Wang, Masakazu Kamata, Juan C. Almagro, Otoniel Martínez-Maza, Manuel L. Penichet
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
AIDS-NHL
antibody therapy
Burkitt lymphoma
CD71
non-Hodgkin lymphoma
transferrin receptor
Online Access:https://www.mdpi.com/2072-6694/15/6/1816

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https://www.mdpi.com/2072-6694/15/6/1816

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