Intestinal organoid modeling: bridging the gap from experimental model to clinical translation

The 3D culture of intestinal organoids entails embedding isolated intestinal crypts and bone marrow mesenchymal stem cells within a growth factor-enriched matrix gel. This process leads to the formation of hollow microspheres with structures resembling intestinal epithelial cells, which are referred...

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Bibliographic Details
Main Authors: Taotao Liu, Xiaoqi Li, Hao Li, Jingjing Qin, Hui Xu, Jun Wen, Yaqin He, Cao Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1334631/full